Prof. Jonas Tegenfeldt, PhD

Solid State Physics

Recent News

Patent granted on DNA labeling scheme based on localized melting

[21 March, 2017]

The US Patent Office has granted a patent (US 9,597,687) for a method to label DNA that was developed in our lab in a collaboration with DTU and Risø National Laboratory in Denmark. The technique gives a barcode pattern along the DNA that can be used to identify fragments of DNA for applications in for example microorganism identification, genome assembly and characterization of structural variations. The technique is described in our paper from 2010 in PNAS.

 

Project on a DNA barcode reader based on a cell phone for diagnostics

[19 January, 2017]

We have been granted funding from the Swedish Research Council to develop and validate a system to identify pathogens and antibiotic resistance relevant for the developing world. The technology is based on reading out barcode patterns along the DNA using e.g. our melting mapping approach combined with cell-phone based microscopy as developed by Aydogan Ozcan at UCLA. The project will take place in a highly international collaboration among researchers from Europe, USA and Africa.

 

Stefan Holm's paper on blood parasites made it to the cover of Analytical Methods

[April, 2016]

Shape based sorting is used to sort out WBC, RBC and parasites from blood using several DLD devices with different array parameters connected in series.

Read more at Abstract Cover

 

Tegenfeldt is chair of the Micro Nano System Workshop organized in Lund 17-18 2016

[January, 2016]

The Micro Nano System Workshop (MSW2016) has been organized every second year for the past 20 years on the theme of micro- and nano-engineering. It covers topics ranging from fundamentals to applications including applications in biology and medicine. New for this year is the opportunity to present live demonstrations. For further details about the meeting, how to submit abstracts and how to plan the demos, please refer to MSW2016.

 

Funding for studies of "Cellmechanics as a biomarker in oncology"

[November, 2015]

We have received a project grant from the Swedish Research Council to develop and validate a system to characterize cancer cells with respect to their mechanical properties, mapping the correlation between the physical properties and the transcriptome as well as the metastatic potential of the cells.

 

Equipment grant for super-resolution microscopy

[June, 2015]

We have received a generous grant for a super-resolution optical microscopy system based on STED and related techniques from the Crafoord Foundation. The instrument is expected to be installed during spring 2016 and made available to a wide range of projects at the university.

 

Scholarship from the Sten K Johnson Foundation 

[May, 2015]

We have received a scholarship for our work on hydrogel based secretion sorting from the Sten K Johnson Foundation.


Current Project Funding

 

Project grant through the Swedish Research Council

"Portable diagnostics for disease and drug resistance with focus on malaria and bacterial infections"

Project grant through the Swedish Research Council

"Cellmechanics as a biomarker in oncology"

Project grant through Horizon2020 / Health

"Genomic diagnostics beyond the sequence (BeyondSeq)"

Project grant through EuroNanoMed

“Nanofluidics for ultrafast diagnosis of bacterial infections (NanoDiaBac)”

Initial Training Network (EU/FP7)

"Label Free Particle Sorting", LAPASO.

Project grant through Barncancerfonden

"Mechanical properties of cancer cells as a marker for diagnosis and prognosis".

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Contact information Lund:

 

Jonas Tegenfeldt


Office Q142
Division of Solid State Physics
Department of Physics
Lund University
Box 118
SE-221 00 Lund
Sweden

Visiting address:
Professorsgatan 1
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Office Phone: +46-(0)46-222 8063 (forwarded to mobile phone)
Fax: +46-(0)46-222 3637
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Optics and fluidics labs (Q129 and Q112)
Soft lithography (PDMS) lab (Q126)
Super resolution microscopy (STED) lab (Q115)

Short CV:


2014 - present Full Professor at Solid State Physics, Lund University

2008-2014 VR-financed "Rådsforskare" (Eng: Senior Research Fellowship Award)

2003-2008 VR-financed "Forskarassistent" (Eng: Assistant Professor)

2007 Docent (Associate Professor) in Solid State Physics

1998 - 2003 PostDoc at Princeton University

1997 PhD in Solid State Physics Lund University

1991 MSc in Engineering Physics / Materials Science Uppsala University

1986 Swedish Defense Institute of Language (Military Service)


Research interests

Micro and nanotechnology to address life science problems.

 

  • Separation science
  • Nanofluidics
  • Polymers in confined environments
  • Tools for single-cell biology
  • Super resolution microscopy (STED)