Review paper on microfluidic isolation of parasites in Pathogens
We published a review paper covering techniques to isolate African trypanosomes in the journal Pathogens together with a consortium financed through the project LAPASO. Abstract.
Tegenfeldt is chair of the Workshop on Labelling and Imaging Techniques in Super-Resolution Microscopy organized in Lund February 5-6 2018
Labelling is considered a major factor influencing the quality and the information obtainable in super-resolution microscopy. The workshop will cover different labelling strategies and imaging modalities along with applications in STED, STORM, FPALM and other types of super resolution microscopy techniques.
Stay tuned for more information!
Trung Tran's paper on open DLD is accepted for publication in Lab on a Chip
A DLD device without cover is demonstrated for sorting of polymer microspheres and different types of cells. The benefit of the open architecture is that the device is easy to clean and less prone to clogging compared to conventional closed microfluidics. The device is driven by a paper capillary pump opening up for applications based on paper fluidics. Abstract.
Tegenfeldt is chair of the European Workshop on Label Free Particle Sorting organized in Lund September 5-6 2017
The Initial Training Network (EU/FP7) "Label Free Particle Sorting", LAPASO, has brought together 15 partners from academia, industry, government and other actors to develop technologies based on microfluidic label free sorting for application in bacteriology, parasitology and rare cells. The project is rounded off by a workshop organized in Lund September 5-6 2017.
Review paper on optical DNA mapping published in BioTechniques
We published a review paper covering optical DNA mapping techniques in BioTechniques together with a consortium financed through the project NanoDiaBac. Abstract.
Patent granted on DNA labeling scheme based on localized melting
[21 March, 2017]
The US Patent Office has granted a patent (US 9,597,687) for a method to label DNA that was developed in our lab in a collaboration with DTU and Risø National Laboratory in Denmark. The technique gives a barcode pattern along the DNA that can be used to identify fragments of DNA for applications in for example microorganism identification, genome assembly and characterization of structural variations. The technique is described in our paper from 2010 in PNAS.
Project on a DNA barcode reader based on a cell phone for diagnostics
[19 January, 2017]
We have been granted funding from the Swedish Research Council to develop and validate a system to identify pathogens and antibiotic resistance relevant for the developing world. The technology is based on reading out barcode patterns along the DNA using e.g. our melting mapping approach combined with cell-phone based microscopy as developed by Aydogan Ozcan at UCLA. The project will take place in a highly international collaboration among researchers from Europe, USA and Africa.
Bao H Dang earned his Licentiate degree after a successful defense
Bao Dang Ho defended hos Licentiate Thesis June 16 2017, entiteled "Deterministic Sorting
by Electrical Properties and Morphology". Opponent was Dr Andreas Dahlin from Chalmers Technical University, Gothenburg, Sweden.
Read more in the Lic thesis
Stefan Holm's paper on blood parasites made it to the cover of Analytical Methods
Shape based sorting is used to sort out WBC, RBC and parasites from blood using several DLD devices with different array parameters connected in series.
Tegenfeldt is chair of the Micro Nano System Workshop organized in Lund May 17-18 2016
The Micro Nano System Workshop (MSW2016) has been organized every second year for the past 20 years on the theme of micro- and nano-engineering. It covers topics ranging from fundamentals to applications including applications in biology and medicine. New for this year is the opportunity to present live demonstrations. For further details about the meeting, how to submit abstracts and how to plan the demos, please refer to MSW2016.
Funding for studies of "Cellmechanics as a biomarker in oncology"
We have received a project grant from the Swedish Research Council to develop and validate a system to characterize cancer cells with respect to their mechanical properties, mapping the correlation between the physical properties and the transcriptome as well as the metastatic potential of the cells.
Equipment grant for super-resolution microscopy
We have received a generous grant for a super-resolution optical microscopy system based on STED and related techniques from the Crafoord Foundation. The instrument is expected to be installed during spring 2016 and made available to a wide range of projects at the university.
Scholarship from the Sten K Johnson Foundation
We have received a scholarship for our work on hydrogel based secretion sorting from the Sten K Johnson Foundation.
Current Project Funding
Project grant through the Swedish Research Council
"Portable diagnostics for disease and drug resistance with focus on malaria and bacterial infections"
Project grant through the Swedish Research Council
"Cellmechanics as a biomarker in oncology"
Project grant through Horizon2020 / Health
"Genomic diagnostics beyond the sequence (BeyondSeq)"
Project grant through EuroNanoMed
“Nanofluidics for ultrafast diagnosis of bacterial infections (NanoDiaBac)”
Initial Training Network (EU/FP7)
"Label Free Particle Sorting", LAPASO.
Project grant through Barncancerfonden
"Mechanical properties of cancer cells as a marker for diagnosis and prognosis".