Prof. Jonas Tegenfeldt, PhD

Solid State Physics

Recent News

Stefan Holm published a study in Physical Review Applied on the effect of hematocrit on the sorting capabilities of DLD.

[26 July 2019]

Particle-particle interactions influence the sorting capability of DLD. Here we have studied the effect of increasing hematocrit on the sorting of microspheres. It was found that microspheres of size much larger and much smaller than the critical size are not affected by the hematocrit while particles close to the critical size exit teh array at an intermediate position. The work was done within the EU project LAPASO in collaboration with the Gompper group at Forschungszentrum Jülich.  Abstract


Jason Beech demonstrated a novel type of DLD array in Advanced materials Technologies.

[11 July 2019]

Active posts in DLD - by making the posts in the DLD array active electrodes we achieve high fields even with minute applied voltages. We demonstrate deflection of nanosclae particles opening up for nanoscale particle separation in devices designed with micrometer featres. The work was done in collaboration with the Guiducci group at EPFL.  Abstract   Cover


Trung Si Hoai Tran successfully defended his thesis entitled Deterministic Lateral Displacement for Cell Separation, 14 June 2019 at 9:15, at the department of Physics (Rydbergsalen). Professor Nikolaj Gadegaard was the opponent.

[14 June, 2019]

Read more in the PhD thesis (pdf)

The two main contributions discussed in the thesis comprise deformablity based sorting of cancer cells, and deterministic lateral displacement on a surface. 


Bao Dang Ho successfully defended his thesis entitled Cell Sorting in Pillar Arrays based on Electrokinetics and Morphology, 23 November 2018 at 9:15, at the department of Physics (Rydbergsalen). Professor Michael Hughes was the opponent.

[November, 2018]

Read more in the PhD thesis (optimized pdf)

The main contribution discussed in the thesis comprises a combination of electrokinetics and deterministic lateral displacement. Fundamental issues are discussed and proof of principle is demonstrated of sorting of bacteria and yeast based on their viability. Both translational and rotation effects are demonstrated. Furthermore, morphological sorting of bacteria is demonstrated.


Tegenfeldt is chair of the Workshop on Labelling and Imaging Techniques in Super-Resolution Microscopy organized in Lund May 28-29 2018

[May, 2018]

Labelling is considered a major factor influencing the quality and the information obtainable in super-resolution microscopy. The workshop will cover different labelling strategies and imaging modalities along with applications in STED, STORM, FPALM and other types of super resolution microscopy techniques.

More information at the website! Click here for detailed program.


Stefan Holm successfully defended his PhD thesis entitled Microfluidic Cell and Particle Sorting using Deterministic Lateral Displacement, 16 March 2018 at 14:15, at the department of Physics (Rydbergsalen). Prof Brian Kirby was the opponent.

[March, 2018]


Read more in the PhD thesis (optimized pdf)

The main contributions discussed in the thesis comprise morphological sorting, specifically with applications in parasite enrichment, density based sorting, fundamental study of the effect of hematocrit in DLD devices, and fabrication of colloidal molecules using droplet fluidics.


Kushagr Punyani successfully defended his Licentiate thesis entitled Label-free particle sorting: technology and biological applications, 14 March 2018 at 10:15, at the department of Physics (H221).  Dr Håkan Jönsson was the opponent.

[March, 2018]


Read more in the Licentiate thesis


Review paper on microfluidic isolation of parasites in Pathogens

[October, 2017]

We published a review paper covering techniques to isolate African trypanosomes in the journal Pathogens together with a consortium financed through the project LAPASO. Abstract.


Trung Tran's paper on open DLD is accepted for publication in Lab on a Chip

[September, 2017]

A DLD device without cover is demonstrated for sorting of polymer microspheres and different types of cells. The benefit of the open architecture is that the device is easy to clean and less prone to clogging compared to conventional closed microfluidics. The device is driven by a paper capillary pump opening up for applications based on paper fluidics. Abstract.


Tegenfeldt is chair of the European Workshop on Label Free Particle Sorting organized in Lund September 5-6 2017

[September, 2017]

The Initial Training Network (EU/FP7) "Label Free Particle Sorting", LAPASO, has brought together 15 partners from academia, industry, government and other actors to develop technologies based on microfluidic label free sorting for application in bacteriology, parasitology and rare cells. The project is rounded off by a workshop organized in Lund September 5-6 2017.


Review paper on optical DNA mapping published in BioTechniques

[June, 2017]

We published a review paper covering optical DNA mapping techniques in BioTechniques together with a consortium financed through the project NanoDiaBac. Abstract.


Patent granted on DNA labeling scheme based on localized melting

[21 March, 2017]

The US Patent Office has granted a patent (US 9,597,687) for a method to label DNA that was developed in our lab in a collaboration with DTU and Risø National Laboratory in Denmark. The technique gives a barcode pattern along the DNA that can be used to identify fragments of DNA for applications in for example microorganism identification, genome assembly and characterization of structural variations. The technique is described in our paper from 2010 in PNAS.


Project on a DNA barcode reader based on a cell phone for diagnostics

[19 January, 2017]

We have been granted funding from the Swedish Research Council to develop and validate a system to identify pathogens and antibiotic resistance relevant for the developing world. The technology is based on reading out barcode patterns along the DNA using e.g. our melting mapping approach combined with cell-phone based microscopy as developed by Aydogan Ozcan at UCLA. The project will take place in a highly international collaboration among researchers from Europe, USA and Africa.


Bao H Dang earned his Licentiate degree after a successful defense

[June, 2017]

Bao Dang Ho defended hos Licentiate Thesis June 16 2017, entiteled "Deterministic Sorting
by Electrical Properties and Morphology". Opponent was Dr Andreas Dahlin from Chalmers Technical University, Gothenburg, Sweden.

Read more in the Lic thesis


Stefan Holm's paper on blood parasites made it to the cover of Analytical Methods

[April, 2016]

Shape based sorting is used to sort out WBC, RBC and parasites from blood using several DLD devices with different array parameters connected in series.

Read more at Abstract Cover


Tegenfeldt is chair of the Micro Nano System Workshop organized in Lund May 17-18 2016

[January, 2016]

The Micro Nano System Workshop (MSW2016) has been organized every second year for the past 20 years on the theme of micro- and nano-engineering. It covers topics ranging from fundamentals to applications including applications in biology and medicine. New for this year is the opportunity to present live demonstrations. For further details about the meeting, how to submit abstracts and how to plan the demos, please refer to MSW2016.


Funding for studies of "Cellmechanics as a biomarker in oncology"

[November, 2015]

We have received a project grant from the Swedish Research Council to develop and validate a system to characterize cancer cells with respect to their mechanical properties, mapping the correlation between the physical properties and the transcriptome as well as the metastatic potential of the cells.


Equipment grant for super-resolution microscopy

[June, 2015]

We have received a generous grant for a super-resolution optical microscopy system based on STED and related techniques from the Crafoord Foundation. The instrument is expected to be installed during spring 2016 and made available to a wide range of projects at the university.


Scholarship from the Sten K Johnson Foundation 

[May, 2015]

We have received a scholarship for our work on hydrogel based secretion sorting from the Sten K Johnson Foundation.

Current Project Funding


Project grant through the Swedish Research Council

"Portable diagnostics for disease and drug resistance with focus on malaria and bacterial infections"

Project grant through the Swedish Research Council

"Cellmechanics as a biomarker in oncology"

Project grant through Horizon2020 / Health

evFOUNDRY, see also announcement.



Selected Past Project Funding

Project grant through Horizon2020 / Health

"Genomic diagnostics beyond the sequence (BeyondSeq)"

Project grant through EuroNanoMed

“Nanofluidics for ultrafast diagnosis of bacterial infections (NanoDiaBac)”

Initial Training Network (EU/FP7)

"Label Free Particle Sorting", LAPASO.

Project grant through Barncancerfonden

"Mechanical properties of cancer cells as a marker for diagnosis and prognosis".


Admin links:

collection of admin tools

nano ftp







study plan



Articles View Hits

Contact information Lund:


Jonas Tegenfeldt

Office Q142
Division of Solid State Physics
Department of Physics
Lund University
Box 118
SE-221 00 Lund

Visiting address:
Professorsgatan 1
Click here for a map!

Office Phone: +46-(0)46-222 8063 (forwarded to mobile phone)
Fax: +46-(0)46-222 3637
This email address is being protected from spambots. You need JavaScript enabled to view it.

Optics and fluidics labs (Q129 and Q112)
Soft lithography (PDMS) lab (Q126)
Super resolution microscopy (STED) lab (Q115)
Microbiology lab (BSL2) (Q262)


Short CV:


2014 - present Full Professor at Solid State Physics, Lund University

2008-2014 VR-financed "Rådsforskare" (Eng: Senior Research Fellowship Award)

2003-2008 VR-financed "Forskarassistent" (Eng: Assistant Professor)

2007 Docent (Associate Professor) in Solid State Physics

1998 - 2003 PostDoc at Princeton University

1997 PhD in Solid State Physics Lund University

1991 MSc in Engineering Physics / Materials Science Uppsala University

1986 Swedish Defense Institute of Language (Military Service)

Research interests

Micro and nanotechnology to address life science problems.


  • Separation science
  • Nanofluidics
  • Polymers in confined environments
  • Tools for single-cell biology
  • Super resolution microscopy (STED)